3/19/2023 0 Comments Osirix md support for pdf filesIn patients in whom metastases are limited to lymph nodes in the thorax, this may reduce costly and invasive procedures such as endobronchial ultrasound or mediastinoscopy procedures. The inclusion of primary tumour data improved the performance of the model, while additional knowledge of distant metastases did not. Using the XGB algorithm potentially leads to an improved model for the classification of intrathoracic lymph nodes. The performance of the model in the test set (centre 2) was slightly but statistically significantly lower than in the validation set (centre 1). Adding the clinical information about distant metastases did not lead to significant improvement. ResultsĪdding primary tumour data resulted in a significant gain in the performance of the trained classifier model. To determine the performance of the model in a different hospital, the XGB model was tested using data from centre 2. Data from centre 1 were used for training and validation of the models using the XGB algorithm. Various scenarios were defined by selecting different combinations of data input and clinical features. From the image data, we extracted radiomic features and trained the classifier model using the extreme gradient boost (XGB) algorithm. Lymph nodes were classified as malignant or benign. The primary tumour and suspected lymph node metastases were annotated and cross-referenced with pathology results. We retrospectively selected lung cancer patients who underwent PET-CT for initial staging in two centres in the Netherlands. The purpose of the current study was to investigate the effect of incorporating primary tumour data and clinical features to differentiate between FDG-avid malignant and benign intrathoracic lymph nodes. FDG PET-CT has an important role in the initial staging of lung cancer however, accurate differentiation between activity in malignant and benign intrathoracic lymph nodes on PET-CT scans can be challenging.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |